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DDX6 antibody

GTX102795
GeneTex
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetDDX6
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Overview

  • Supplier
    GeneTex
  • Product Name
    DDX6 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.71 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID1656
  • Target name
    DDX6
  • Target description
    DEAD-box helicase 6
  • Target synonyms
    HLR2, IDDILF, P54, RCK, Rck/p54, probable ATP-dependent RNA helicase DDX6, putative ATP-dependent RNA helicase DDX6, ATP-dependent RNA helicase p54, DEAD (Asp-Glu-Ala-Asp) box helicase 6, DEAD (Asp-Glu-Ala-Asp) box polypeptide 6, DEAD box protein 6, DEAD box-6, DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 6 (RNA helicase, 54kD), oncogene RCK
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP26196
  • Protein Name
    Probable ATP-dependent RNA helicase DDX6
  • Scientific Description
    This gene encodes a member of the DEAD box protein family. The protein is an RNA helicase found in P-bodies and stress granules, and functions in translation suppression and mRNA degradation. It is required for microRNA-induced gene silencing. [provided by RefSeq]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Arora R, Bodak M, Penouty L, et al. Sequestration of LINE-1 in cytosolic aggregates by MOV10 restricts retrotransposition. EMBO Rep. 2022,23(9):e54458. doi: 10.15252/embr.202154458
    Read this paper
  • Maeda R, Kami D, Shikuma A, et al. RNA decay in processing bodies is indispensable for adipogenesis. Cell Death Dis. 2021,12(4):285. doi: 10.1038/s41419-021-03537-7
    Read this paper
  • Bearss JJ, Padi SK, Singh N, et al. EDC3 phosphorylation regulates growth and invasion through controlling P-body formation and dynamics. EMBO Rep. 2021,22(4):e50835. doi: 10.15252/embr.202050835
    Read this paper
  • Duan Z, Ping P, Wang G, et al. Imsnc761 and DDX6 synergistically suppress cell proliferation and promote apoptosis via p53 in testicular embryonal carcinoma cells. Biosci Rep. 2018,38(4):pii: BSR20180271. doi: 10.1042/BSR20180271.
    Read this paper
  • Sundararaman B, Zhan L, Blue SM, et al. Resources for the Comprehensive Discovery of Functional RNA Elements. Mol Cell. 2016,61(6):903-13. doi: 10.1016/j.molcel.2016.02.012
    Read this paper