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ProductsBack/Defactinib HCl [1073160-26-5] [1073160-26-5]

Defactinib HCl [1073160-26-5] [1073160-26-5]

BS-7055C
Bioss
CAS Number1073160-26-5
Product group Chemicals
Estimated Purity98 - 98.0
Molecular Weight546.95
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Overview

  • Supplier
    Bioss
  • Product Name
    Defactinib HCl [1073160-26-5] [1073160-26-5]
  • Delivery Days Customer
    16
  • CAS Number
    1073160-26-5
  • Certification
    Research Use Only
  • Conjugate
    Unconjugated
  • Estimated Purity
    98 - 98.0
  • Molecular Formula
    C20 H22 Cl F3 N8 O3 S
  • Molecular Weight
    546.95
  • Scientific Description
    Defactinib, also known as VS-6063 and PF-04554878, is an orally bioavailable, small-molecule focal adhesion kinase (FAK) inhibitor with potential antiangiogenic and antineoplastic activities. FAK inhibitor PF-04554878 inhibits FAK, which may prevent the integrin-mediated activation of several downstream signal transduction pathways, including ERK, JNK/MAPK and PI3K/Akt, thus inhibiting tumor cell migration, proliferation and survival.
  • SMILES
    Cl.CNC(=O)C1C=CC(=CC=1)NC1N=C(NCC2=NC=CN=C2N(C)S(C)(=O)=O)C(=CN=1)C(F)(F)F
  • Storage Instruction
    -20°C
  • UNSPSC
    12161509

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