Delavirdine

MedChem Express

Delavirdine [136817-59-9]

10

136817-59-9

Research Use Only

99.60

C22H28N6O3S

456.56

Delavirdine (U 90152) is a potent, highly specific and orally active non-nucleoside reverse transcriptase inhibitor (NNRTI). Delavirdine selectively inhibits HIV-1 reverse transcriptase (RT) ( IC 50 =0.26?microM) over DNA polymerase?alpha?(IC 50 =440 microM) and polymerase?delta (IC 50 >550?microM). Delavirdine is an inhibitor of HIV-1 replication and can can be used for the study of AIDs [1] .

O=S(NC1=CC=C(NC(C(N2CCN(C3=C(NC(C)C)C=CC=N3)CC2)=O)=C4)C4=C1)(C)=O

-20°C,2°C to 8°C

12352200