Dendrogenin A [1191043-85-2]

MedChem Express

Dendrogenin A [1191043-85-2]

9

1191043-85-2

Research Use Only

96.7

C32H55N3O2

513.80

Dendrogenin A (DDA) is a ligand for liver X receptor (LXR), that induces the expression of sodium/iodine symporter, and increases iodine uptake. Dendrogenin A induces cell differentiation of MCF-7, and reactivates the function of lactating cells. Dendrogenin A induces the expressions of the TSH receptor, thyroid peroxidase, and thyroglobulin, and affects thyroid hormone generation. Dendrogenin A exhibits cytotoxicity in cancer cell B-CPAP and 8505c with IC50 of 4.1 and 6.2 microM. Dendrogenin A arrests the cell cycle at G0/G1 phase[1].

C[C@@]12[C@]3([H])[C@](C[C@H]([C@]1(C[C@H](CC2)O)O)NCCC4=CN=CN4)([H])[C@@]5([H])[C@](CC3)([C@@](CC5)([H])[C@H](C)CCCC(C)C)C

-20°C,2°C to 8°C

12131703