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Denfivontinib [1457983-28-6]

HY-12333
MedChem Express
CAS Number1457983-28-6
Product group Chemicals
Estimated Purity98.0
Molecular Weight521.41
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Denfivontinib [1457983-28-6]
  • Delivery Days Customer
    10
  • CAS Number
    1457983-28-6
  • Certification
    Research Use Only
  • Estimated Purity
    98.0
  • Molecular Formula
    C25H25BrN6O2
  • Molecular Weight
    521.41
  • Scientific Description
    Denfivontinib (G-749) is a potent, oral active and ATP competitive FLT3 inhibitor, with IC50s of 0.4 nM and 0.6 nM for FLT3 wild type and FLT3-D835Y, respectively. Denfivontinib can be used for the research of agent resistance for acute myeloid leukemia (AML)[1].
  • SMILES
    O=C1NC=C(C2=C1C(NC3=CC=C(C=C3)OC4=CC=CC=C4)=NC(NC5CCN(CC5)C)=N2)Br
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200

MSDS

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