WB analysis of human fetal muscle tissue using GTX44900 DENND1A antibody at 0.2-1microg/ml.
WB analysis of human fetal muscle tissue using GTX44900 DENND1A antibody at 0.2-1microg/ml.
DENND1A antibody, N-term
GTX44900
Overview
- SupplierGeneTex
- Product NameDENND1A antibody, N-term
- Delivery Days Customer9
- Application Supplier NoteWB: 0.2-2.5 ug/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.5-1 mg/ml
- ConjugateUnconjugated
- Gene ID57706
- Target nameDENND1A
- Target descriptionDENN domain containing 1A
- Target synonymsconnecdenn 1; DENN domain-containing protein 1A; DENN/MADD domain containing 1A; FAM31A; KIAA1608
- HostRabbit
- IsotypeIgG
- Protein IDQ8TEH3
- Protein NameDENN domain-containing protein 1A
- Scientific DescriptionClathrin (see MIM 118955)-mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family, such as DENND1A, function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 (MIM 604199) and bind to clathrin and clathrin adaptor protein-2 (AP2; see MIM 601024). Thus, connecdenns link RAB35 activation with the clathrin machinery (Marat and McPherson, 2010 [PubMed 20154091]).[supplied by OMIM, Nov 2010]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203