Denosumab

MedChem Express

Denosumab [615258-40-7]

10

Research Use Only

Monoclonal

99.10

Denosumab is a human monoclonal antibody that targets the protein RANKL. Denosumab binds to the receptor activator of nuclear factor kappa-B ligand (RANKL) and prevents its binding to the RANK receptor ( K D of 0.003 nM for human RANKL). Denosumab promotes proliferation and spermatogenesis. Denosumab prevents bone resorption through inhibition of the NF-kappaB pathway. Denosumab can be used in bone-related studies [1] [2] [3] [4] [5] [6] [7] .

2°C to 8°C

12352203