Deoxypodophyllotoxin

MedChem Express

Deoxypodophyllotoxin [19186-35-7]

9

19186-35-7

Research Use Only

99.87

C22H22O7

398.41

Deoxypodophyllotoxin (DPT), a derivative of podophyllotoxin, is a lignan with potent antimitotic, anti-inflammatory and antiviral properties isolated from Anthriscus sylvestris . Deoxypodophyllotoxin, targets the microtubule , has a major impact in oncology not only as anti-mitotics but also as potent inhibitors of angiogenesis [1] . Deoxypodophyllotoxin induces cell autophagy and apoptosis [2] . Deoxypodophyllotoxin evokes increase of intracellular Ca 2+ concentrations in DRG neurons [3] .

O=C1[C@]2([H])[C@H](C3=CC(OC)=C(OC)C(OC)=C3)C4=CC(OCO5)=C5C=C4C[C@@]2([H])CO1

-20°C,2°C to 8°C

12352200