Deoxyviolacein [5839-61-2]

MedChem Express

Deoxyviolacein [5839-61-2]

5

5839-61-2

Research Use Only

C20H13N3O2

327.34

Deoxyviolacein is a bacterial metabolite and byproduct in the biosynthesis of the bisindole alkaloid violacein (HY-119809) that has anticancer, antibacterial, and antifungal properties. It inhibits proliferation of hepatocellular carcinoma cells when used at concentrations ranging from 0.1 to 1 microM. Deoxyviolacein (125 microg/mL) has antibacterial activity against Gram-positive bacteria, including S. aureus, B. subtilis, and B. megaterium. It also has antifungal activity against R. solani when used at a concentration of 2 mg/ml.

O=C1NC(C=CC=C2)=C2/C1=C3C(NC(C4=CNC5=C4C=CC=C5)=C\3)=O

12352200