Derenofylline [251945-92-3]

MedChem Express

Derenofylline [251945-92-3]

9

251945-92-3

Research Use Only

99.93

C18H20N4O

308.38

Derenofylline (SLV 320) is a potent, selective and orally active adenosine A1 receptor antagonist, with Ki values of 1 nM, 200 nM and 398 nM for human A1, A3 and A2A receptors respectively. Derenofylline suppresses cardiac fibrosis and attenuates albuminuria without affecting blood pressure in rats[1].

O[C@H]1CC[C@H](NC2=C3C(NC=C3)=NC(C4=CC=CC=C4)=N2)CC1

-20°C,2°C to 8°C

12352200