(Des-Bromo)-Neuropeptide B (1-23) (human)

Biorbyt

(Des-Bromo)-Neuropeptide B (1-23) (human)

10

Research Use Only

98.00%

C107H162N30O30

2348.61

(Des-Bromo)-Neuropeptide B (1-23) (human) is an agonist for orphan G-protein-coupled receptors, exhibiting a K i of 1.2 nM for GPR7 (NPBW1) and 341 nM for GPR8 (NPBW2) respectively [1].

C([C@@H](C(N[C@@H](CC1=CC=C(O)C=C1)C(N[C@H](C(=O)N2[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@@H](CC3=CN=CN3)C(N[C@H](C(N[C@H](C(N[C@@H](CC4=CC=C(O)C=C4)C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@@H](CC(C)C)C(O)=O)=O)=O)CO)=O)CC(C)C)=O)CC(C)C)=O)=O)C)=O)C)=O)CCCNC(=N)N)=O)=O)[C@@H](C)C)=O)CO)=O)=O)CO)=O)CO)=O)=O)=O)C)=O)C)=O)CCC2)CCCCN)=O)=O)N)C=5C=6C(NC5)=CC=CC6

-20°C

12352200