Deschloroclozapine (dihydrochloride)

MedChem Express

Deschloroclozapine (dihydrochloride)

14

Research Use Only

99.87

C18H22Cl2N4

365.30

Deschloroclozapine dihydrochloride, a metabolite of Clozapine, is a highly potent muscarinic DREADDs agonist. Deschloroclozapine binds to DREADD receptor subtypes hM3Dq and hM4Di with K i of 6.3 and 4.2 nM, respectively. [ 11 C]-Deschloroclozapine is developed as a promising PET tracer for DREADD imaging [1] [2] [3] .

CN1CCN(C2=NC3=CC=CC=C3NC4=CC=CC=C42)CC1.[H]Cl.[H]Cl

-20°C

12352200