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Desloratadine

HY-B0539
MedChem Express
CAS Number100643-71-8
Product group Chemicals
Estimated Purity99.98
Molecular Weight310.828
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Desloratadine [100643-71-8]
  • Delivery Days Customer
    5
  • CAS Number
    100643-71-8
  • Certification
    Research Use Only
  • Estimated Purity
    99.98
  • Molecular Formula
    C19H19ClN2
  • Molecular Weight
    310.828
  • Scientific Description
    Desloratadine (Sch34117) is an orally active and selective H1 receptor antagonist (Ki=0.9 nM) with anti-inflammatory and anti-allergic activities. Desloratadine inhibits the release of histamine and LTC4 from human basophils and targets the regulatory signals of IL-4 and IL-13 production in basophils. Desloratadine significantly alleviates SAR symptoms in patients with concurrent asthma and can be used in the study of seasonal allergic rhinitis and chronic idiopathic urticaria[1][2][3][4][5][6].
  • SMILES
    ClC1=CC=C2C(CCC3=CC=CN=C3/C2=C4CCNCC/4)=C1
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200

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