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ProductsBack/Desmethylazelastine [47491-38-3]

Desmethylazelastine [47491-38-3]

HY-147336

CAS Number47491-38-3

Product group Chemicals

Molecular Weight367.87

Overview

Supplier
MedChem Express
Product Name
Desmethylazelastine [47491-38-3]
Delivery Days Customer
10
CAS Number
47491-38-3
Certification
Research Use Only
Molecular Formula
C21H22ClN3O
Molecular Weight
367.87
Scientific Description
Desmethylazelastine is a main active metabolite of Azelastine that is oxidatively metabolized by the cytochrome P450 enzyme system with a protein binding rate of 97% and an elimination half-life of 54 hours. Azelastine is an orally active, selective and high-affinity histamine H1-receptor antagonist. Azelastine can be used in studies of allergic rhinitis, asthma, diabetic hyperlipidemic and SARS-CoV-2[1][2][3][4][5].
SMILES
O=C1C2=C(C(CC3=CC=C(C=C3)Cl)=NN1C4CCNCCC4)C=CC=C2
UNSPSC
12131703

MSDS

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