Desmoglein 1 antibody [3G131]

GeneTex

Desmoglein 1 antibody [3G131]

9

Does not crossreact with desmoglein-2 or desmoglein-3 protein.

ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry

Research Use Only

Monoclonal

3G131

Unconjugated

DSG1

desmoglein 1

cadherin family member 4; CDHF4; desmoglein-1; desmosomal glycoprotein 1; DG1; DSG; EPKHE; EPKHIA; pemphigus foliaceus antigen; PPKS1; SPPK1

Mouse

IgG1

Desmoglein-1

This gene encodes a member of the desmoglein protein subfamily. Desmogleins, along with desmocollins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmoglein family members on chromosome 18. The encoded protein has been identified as a target of auto-antibodies in the autoimmune skin blistering disease pemphigus foliaceus. Disruption of this gene has also been associated with the skin diseases palmoplantar keratoderma and erythroderma. [provided by RefSeq, Feb 2015]

Human

-20°C or -80°C,2°C to 8°C

12352203