Desmoglein 1 antibody [MSVA-544M] HistoMAX(tm)

GeneTex

Desmoglein 1 antibody [MSVA-544M] HistoMAX(tm)

9

IHC-P: 1:75-1:150. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Monoclonal

MSVA-544M

0.2 mg/ml

Unconjugated

DSG1

desmoglein 1

CDHF4, DG1, DSG, EPKHE, EPKHIA, PPKS1, SPPK1, desmoglein-1, cadherin family member 4, desmosomal glycoprotein 1, pemphigus foliaceus antigen

Mouse

IgG2a

Desmoglein-1

This gene encodes a member of the desmoglein protein subfamily. Desmogleins, along with desmocollins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmoglein family members on chromosome 18. The encoded protein has been identified as a target of auto-antibodies in the autoimmune skin blistering disease pemphigus foliaceus. Disruption of this gene has also been associated with the skin diseases palmoplantar keratoderma and erythroderma. [provided by RefSeq, Feb 2015]

Human

-20°C or -80°C,2°C to 8°C

12352203