Desthiobiotin-PEG3-NHS ester [2411681-92-8]

MedChem Express

Desthiobiotin-PEG3-NHS ester [2411681-92-8]

5

Research Use Only

C23H38N4O9

514.57

Desthiobiotin-PEG3-NHS ester is a single-ring, sulfur-free analog of biotin that binds to streptavidin with nearly equal specificity but less affinity than biotin (Kd = 1011 vs. 1015 M, respectively). Consequently, desthiobiotinylated proteins can be eluted readily and specifically from streptavidin affinity resin using mild conditions based on competitive displacement with free biotin.

O=C(N[C@H]1C)N[C@@H]1CCCCCC(NCCOCCOCCOCCC(ON2C(CCC2=O)=O)=O)=O

12352200