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Desvenlafaxine (succinate hydrate) [386750-22-7]

HY-B0602A
MedChem Express
CAS Number386750-22-7
Product group Chemicals
Estimated Purity99.82
Molecular Weight399.48
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Desvenlafaxine (succinate hydrate) [386750-22-7]
  • Delivery Days Customer
    9
  • CAS Number
    386750-22-7
  • Certification
    Research Use Only
  • Estimated Purity
    99.82
  • Molecular Formula
    C20H33NO7
  • Molecular Weight
    399.48
  • Scientific Description
    Desvenlafaxine succinate hydrate, the succinate salt form of the isolated major active metabolite of Venlafaxine (HY-B0196), is an orally active and BBB penetrated 5-HT and norepinephrine reuptake inhibitor, with IC50 values of 47.3 nM and 531.3 nM for hSERT and hNET, respectively. Desvenlafaxine succinate hydrate shows weak binding affinity (62% inhibition at 100 microM) at the human dopamine (DA) transporter[1][2].
  • SMILES
    OC1=CC=C(C(C2(O)CCCCC2)CN(C)C)C=C1.O=C(O)CCC(O)=O.O
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352200