DETD-35
ORB2663556
Estimated Purity98.00%
Product group Chemicals
Molecular Weight444.48
Overview
- SupplierBiorbyt
- Product NameDETD-35
- Delivery Days Customer10
- CertificationResearch Use Only
- Estimated Purity98.00%
- Molecular FormulaC27H24O6
- Molecular Weight444.48
- Scientific DescriptionDETD-35 is a promising chemical compound in anti-melanoma therapy, functioning as an inhibitor of the MEK-ERK, Akt, and STAT3 signaling pathways. It enhances cancer cell apoptosis (Apoptosis) and diminishes resistance to Vemurafenib in cancer cells. The compound exhibits IC 50 values of 2.7, 6.0, 3.9, 3.1, and 2.5 microM against melanoma cell lines B16-F10, MeWo, SK-MEL-2, A2058c, and A375c, respectively. DETD-35 offers significant potential for advancing research in melanoma treatment strategies.
- SMILESC\C1=C\[C@@H](OC(=O)CC2=C3C=CC=CC3=CC=C2)[C@H]2[C@H](CC3=C[C@@H](C1)OC3=O)OC(=O)C2=C
- Storage Instruction-20°C
- UNSPSC12352200