DETQ [1638667-81-8]
HY-115553
CAS Number1638667-81-8
Product group Chemicals
Molecular Weight422.34
Overview
- SupplierMedChem Express
- Product NameDETQ [1638667-81-8]
- Delivery Days Customer10
- CAS Number1638667-81-8
- CertificationResearch Use Only
- Molecular FormulaC22H25Cl2NO3
- Molecular Weight422.34
- Scientific DescriptionDETQ is a selective, allosteric and orally active dopamine D1 receptor (Dopamine Receptor) potentiator. In HEK293 cells expressing the human D1 receptor, DETQ increases cAMP with an EC50 of 5.8 nM and a Kb of 26 nM. DETQ shows ~30-fold less potent at rat and mouse D1 receptors and is inactive at the human D5 receptor[1].
- SMILESC[C@@H]1N(C(CC2=C(Cl)C=CC=C2Cl)=O)[C@@H](CO)CC3=C1C=CC=C3C(C)(O)C
- UNSPSC12352200