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Deucravacitinib (hydrochloride) [1609392-28-0]

HY-117287A
MedChem Express
CAS Number1609392-28-0
Product group Chemicals
Molecular Weight461.92
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Deucravacitinib (hydrochloride) [1609392-28-0]
  • Delivery Days Customer
    9
  • CAS Number
    1609392-28-0
  • Certification
    Research Use Only
  • Molecular Formula
    C20H20D3ClN8O3
  • Molecular Weight
    461.92
  • Scientific Description
    Deucravacitinib hydrochloride (BMS-986165 hydrochloride) is a highly selective all-site inhibitor with potent inhibitory activity against TYK2. Deucravacitinib hydrochloride can effectively block IL-12, IL-23 and type I interferon signaling. Deucravacitinib hydrochloride demonstrates significant efficacy in preclinical models of inflammatory bowel disease. Deucravacitinib hydrochloride demonstrated superiority over placebo and apremilast on multiple efficacy endpoints in moderate to severe plaque psoriasis. Deucravacitinib hydrochloride was well tolerated in inhibition[1].
  • SMILES
    COC1=C(C2=NN(C)C=N2)C=CC=C1NC3=C(N=NC(NC(C4CC4)=O)=C3)C(NC([2H])([2H])[2H])=O.Cl
  • UNSPSC
    12352200