Dezapelisib [1262440-25-4]

TargetMol Chemicals

Dezapelisib [1262440-25-4]

86

Chemical

Research Use Only

Dezapelisib

C20H16FN7OS

421.45

Dezapelisib is an orally bioavailable, selective inhibitor of the delta isoform of the 110 kDa catalytic subunit of class I phosphoinositide-3 kinases (PI3K). INCB040093 prevents both the production of the second messenger phosphatidylinositol-3,4,5-trisphosphate (PIP3) and the activation of the PI3K/AKT kinase signaling pathway. This decreases proliferation and induces cell death in PI3K-overexpressing tumor cells.

3 years

[C@H](NC1=C2C(N=CN2)=NC=N1)(C)C3=C(C(=O)N4C(=N3)SC=C4C)C5=CC(F)=CC=C5

-20°C

12352200