DG1

MedChem Express

DG1

14

Research Use Only

C19H17N5O5S

427.43

DG1 (Compound 8Nc) is a Thymidylate Synthase (TS) inhibitor that affects cancer angiogenesis and metabolic reprogramming in NSCLC cells. DG1 can effectively inhibit the expression of CD26, ET-1, FGF-1 and EGF. DG1 also effectively inhibits the proliferation of cancer tissue in the A549 xenograft mouse model[1].

O=C1NC(NC=C1S(=O)(NC2=CC=CC(C(N/N=C/C3=CC(C)=CC=C3)=O)=C2)=O)=O

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