DGKalpha-IN-8 [2886717-70-8]

TargetMol Chemicals

DGKalpha-IN-8 [2886717-70-8]

16

Research Use Only

DGKalfa-IN-8

C23H19ClF3N5O

473.88

DGKalpha-IN-8 (Example 51), a potent diacylglycerol kinase alpha (DGKalpha) inhibitor, exhibits an IC50 of 22.491 nM and an EC50 of 0.256 nM. It is applicable in cancer research, particularly for solid tumors, and in studies of viral infections such as HIV and hepatitis B virus [1].

3 years

N(CC(F)F)(C=1C=2C(C3=C(N1)N=NN3C)=CC(Cl)=CC2)C4=CC(C#CC(C)(C)O)=CC(F)=C4

-20°C

51202000