DHFR-IN-5 [1142407-81-5]

TargetMol Chemicals

DHFR-IN-5 [1142407-81-5]

72

Chemical

Research Use Only

DHFR-IN-5

C18H24N4O4

360.41

DHFR-IN-5, an orally active and potent inhibitor of dihydrofolate reductase (DHFR), exhibits a K_i value of 0.54 nM against the quadruple mutant Plasmodium falciparum DHFR, demonstrating anti-malarial activity.

3 years

O(CCCOC1=C(CCC(O)=O)C=CC=C1)C=2C(CC)=NC(N)=NC2N

-20°C

51202000