Bio-Connect

DHFR-IN-5 (hydrochloride) [1142407-60-0]

HY-153007A
MedChem Express
CAS Number1142407-60-0
Product group Chemicals
Molecular Weight396.87
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Overview

  • Supplier
    MedChem Express
  • Product Name
    DHFR-IN-5 (hydrochloride) [1142407-60-0]
  • Delivery Days Customer
    9
  • CAS Number
    1142407-60-0
  • Certification
    Research Use Only
  • Molecular Formula
    C18H25ClN4O4
  • Molecular Weight
    396.87
  • Scientific Description
    DHFR-IN-5 hydrochloride is a potent and orally active dihydrofolate reductase (DHFR) inhibitor with a Ki value of 0.54 nM for quadruple mutant Plasmodium falciparum DHFR. DHFR-IN-5 hydrochloride shows anti-malaria activity[1].
  • SMILES
    O=C(CCC1=C(OCCCOC2=C(CC)N=C(N)N=C2N)C=CC=C1)O.Cl
  • UNSPSC
    12352200