DHFR-IN-8

Biorbyt

DHFR-IN-8

10

Research Use Only

98.00%

C18H14N6S

346.41

DHFR-IN-8 (compound 6r), a dihydrofolate reductase (DHFR) inhibitor, disrupts purine and thymidylate biosynthesis critical for cell proliferation and growth. This compound effectively suppresses methicillin-resistant Staphylococcus aureus (MRSA) ATCC 43300 with an IC50 of 15.6 ng/mL in mouse models of systemic and thigh infections [1].

-20°C

12352200