DHFR-IN-8

TargetMol Chemicals

DHFR-IN-8

999

Chemical

Research Use Only

DHFR-IN-8

C18H14N6S

346.41

DHFR-IN-8 (compound 6r), a dihydrofolate reductase (DHFR) inhibitor, disrupts purine and thymidylate biosynthesis critical for cell proliferation and growth. This compound effectively suppresses methicillin-resistant Staphylococcus aureus (MRSA) ATCC 43300 with an IC50 of 15.6 ng/mL in mouse models of systemic and thigh infections [1].

3 years

-20°C

51202000