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GTX109762 WB Image
GTX109762 WB Image
GTX109762 WB Image

Dhh antibody [N3C3]

Research Use Only
GTX109762
GeneTex
Product group Antibodies
Price on request
Packing Size
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Overview

  • Supplier
    GeneTex
  • Product Name
    Dhh antibody [N3C3]
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Concentration
    0.95 mg/ml
  • Isotype
    IgG
  • Scientific Description
    This gene encodes a member of the Hedgehog family. The hedgehog gene family encodes signaling molecules that play an important role in regulating morphogenesis. This protein is predicted to be made as a precursor that is autocatalytically cleaved; the N-terminal portion is soluble and contains the signalling activity while the C-terminal portion is involved in precursor processing. More importantly, the C-terminal product covalently attaches a cholesterol moiety to the N-terminal product, restricting the N-terminal product to the cell surface and preventing it from freely diffusing throughout the organism. Defects in this protein have been associated with partial gonadal dysgenesis (PGD) accompanied by minifascicular polyneuropathy. This protein may be involved in both male gonadal differentiation and perineurial development. [provided by RefSeq]
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203

References

  • Ciliary Hedgehog Signaling Restricts Injury-Induced Adipogenesis. Kopinke D et al., 2017 Jul 13, Cell
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