DHODH-IN-4 [1148125-93-2]

MedChem Express

DHODH-IN-4 [1148125-93-2]

10

1148125-93-2

Research Use Only

C17H12Cl2N2O2

347.20

DHODH-IN-4 (compound 17) is a human and Plasmodium falciparum dihydroorotate dehydrogenase (DHODH) inhibitor, with IC50 values of 4 microM and 0.18 microM for PfDHODH and HsDHODH, respectively. DHODH-IN-4 (compound 17) possess antimalarial activity[1].

C/C(O)=C(C#N)/C(NC1=CC=C(C2=CC=CC=C2Cl)C=C1Cl)=O

12352200