DHPS-IN-2

MedChem Express

DHPS-IN-2

5

Research Use Only

C17H15IN2O2

406.22

DHPS-IN-2 is an allosteric deoxyhypusine synthase (DHPS) inhibitor with an IC50 of 70 nM and a Kd of 26.4 microM. DHPS-IN-2 significantly suppresses melanoma cell migration and invasiveness in vitro and exhibits potent anti-tumor efficacy in an A375 cell zebrafish xenograft model. DHPS-IN-2 can be used for the study of melanoma[1].

IC1=CC=C(C=C1)CC2=NN=C(CC3=CC=CC=C3OC)O2

12352200