WB analysis of various sample lysates using GTX32561 DHTKD1 antibody. Dilution : 1:1000 Loading : 25μg per lane
WB analysis of various sample lysates using GTX32561 DHTKD1 antibody. Dilution : 1:1000 Loading : 25μg per lane
DHTKD1 antibody
GTX32561
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetDHTKD1
Overview
- SupplierGeneTex
- Product NameDHTKD1 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500 - 1:2000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID55526
- Target nameDHTKD1
- Target descriptiondehydrogenase E1 and transketolase domain containing 1
- Target synonymsAAKAD, AMOXAD, CMT2Q, E1a, OADC-E1, OADH-E1, 2-oxoadipate dehydrogenase complex component E1, 2-oxoadipate dehydrogenase, mitochondrial, alpha-KADH-E1, alpha-ketoadipate dehydrogenase, dehydrogenase E1 and transketolase domain-containing protein 1, probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial
- HostRabbit
- IsotypeIgG
- Protein IDQ96HY7
- Protein Name2-oxoadipate dehydrogenase complex component E1
- Scientific DescriptionThis gene encodes a component of a mitochondrial 2-oxoglutarate-dehydrogenase-complex-like protein involved in the degradation pathways of several amino acids, including lysine. Mutations in this gene are associated with 2-aminoadipic 2-oxoadipic aciduria and Charcot-Marie-Tooth Disease Type 2Q. [provided by RefSeq, May 2013]
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC41116161
References
- Structure-function analyses of the G729R 2-oxoadipate dehydrogenase genetic variant associated with a disorder of l-lysine metabolism. Zhang X et al., 2020 Jun 5, J Biol ChemRead this paper
- DHTKD1 and OGDH display substrate overlap in cultured cells and form a hybrid 2-oxo acid dehydrogenase complex in vivo. Leandro J et al., 2020 May 8, Hum Mol GenetRead this paper
- Mild inborn errors of metabolism in commonly used inbred mouse strains. Leandro J et al., 2019 Apr, Mol Genet MetabRead this paper
Datasheet
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