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WB analysis of various sample lysates using GTX32561 DHTKD1 antibody. Dilution : 1:1000 Loading : 25microg per lane

DHTKD1 antibody

Name: DHTKD1 antibody
SKU: GTX32561_G10
Availability: BackOrder

GTX32561

ApplicationsWestern Blot

Product group Antibodies

TargetDHTKD1

Overview

Supplier
GeneTex
Product Name
DHTKD1 antibody
Delivery Days Customer
9
Application Supplier Note
WB: 1:500 - 1:2000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Applications
Western Blot
Certification
Research Use Only
Clonality
Polyclonal
Conjugate
Unconjugated
Gene ID55526
Target name
DHTKD1
Target description
dehydrogenase E1 and transketolase domain containing 1
Target synonyms
AAKAD, AMOXAD, CMT2Q, E1a, OADC-E1, OADH-E1, 2-oxoadipate dehydrogenase complex component E1, 2-oxoadipate dehydrogenase, mitochondrial, alpha-KADH-E1, alpha-ketoadipate dehydrogenase, dehydrogenase E1 and transketolase domain-containing protein 1, probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial
Host
Rabbit
Isotype
IgG
Protein IDQ96HY7
Protein Name
2-oxoadipate dehydrogenase complex component E1
Scientific Description
This gene encodes a component of a mitochondrial 2-oxoglutarate-dehydrogenase-complex-like protein involved in the degradation pathways of several amino acids, including lysine. Mutations in this gene are associated with 2-aminoadipic 2-oxoadipic aciduria and Charcot-Marie-Tooth Disease Type 2Q. [provided by RefSeq, May 2013]
Storage Instruction
-20°C or -80°C,2°C to 8°C
UNSPSC
12352203

Zhang X, Nemeria NS, Leandro J, et al. Structure-function analyses of the G729R 2-oxoadipate dehydrogenase genetic variant associated with a disorder of l-lysine metabolism. J Biol Chem. 2020,295(23):8078-8095. doi: 10.1074/jbc.RA120.012761
Read this paper
Leandro J, Dodatko T, Aten J, et al. DHTKD1 and OGDH display substrate overlap in cultured cells and form a hybrid 2-oxo acid dehydrogenase complex in vivo. Hum Mol Genet. 2020,29(7):1168-1179. doi: 10.1093/hmg/ddaa037
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Leandro J, Violante S, Argmann CA, et al. Mild inborn errors of metabolism in commonly used inbred mouse strains. Mol Genet Metab. 2019,126(4):388-396. doi: 10.1016/j.ymgme.2019.01.021
Read this paper