DI-591 [2245887-38-9]
T11033
CAS Number2245887-38-9
Product group Chemicals
Molecular Weight585.8
Overview
- SupplierTargetMol Chemicals
- Product NameDI-591 [2245887-38-9]
- Delivery Days Customer86
- CAS Number2245887-38-9
- CertificationResearch Use Only
- Chemical NameDI-591
- Molecular FormulaC31H47N5O4S
- Molecular Weight585.8
- Scientific DescriptionDI-591 is an effective, high-affinity and cell-permeability inhibitor for DCN1-UBC12 interaction. DI-591 binds to DCN1 and DCN2 with Ki values of 12 and nM and 10.4 nM, respectively, and has no obvious binding to DCN3, DCN4 and DCN5 proteins.
- Shelf life instruction3 years
- SMILESCCC(=O)N[C@@H](Cc1nc2ccc(cc2s1)C(C)C)C(=O)N[C@H](CNC(=O)CCN1CCOCC1)C1CCCCC1
- Storage Instruction-20°C
- UNSPSC12352200
References
- Zhou H, Lu J, Liu L, et al. A potent small-molecule inhibitor of the DCN1-UBC12 interaction that selectively blocks cullin 3 neddylation. Nat Commun. 2017,8(1):1150. doi: 10.1038/s41467-017-01243-7Read this paper
MSDS
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