More than 130 suppliers
ISO certified
In-house tech support
we Connect you
Bio-Connect
ProductsBack/DI-591 [2245887-38-9]
DI-591 [2245887-38-9]

DI-591 [2245887-38-9]

Research Use Only
T11033
TargetMol Chemicals
CAS Number2245887-38-9
DownloadMSDS
Product group Chemicals
Molecular Weight585.8
Sign in to order and to see your custom pricing.
Large volume orders?
Order with a bulk request
More than 130 suppliers
ISO certified
In-house tech support

Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    DI-591 [2245887-38-9]
  • Delivery Days Customer
    86
  • CAS Number
    2245887-38-9
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    DI-591
  • Molecular Formula
    C31H47N5O4S
  • Molecular Weight
    585.8
  • Scientific Description
    DI-591 is an effective, high-affinity and cell-permeability inhibitor for DCN1-UBC12 interaction. DI-591 binds to DCN1 and DCN2 with Ki values of 12 and nM and 10.4 nM, respectively, and has no obvious binding to DCN3, DCN4 and DCN5 proteins.
  • Shelf life instruction
    3 years
  • SMILES
    CCC(=O)N[C@@H](Cc1nc2ccc(cc2s1)C(C)C)C(=O)N[C@H](CNC(=O)CCN1CCOCC1)C1CCCCC1
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

References

  • A potent small-molecule inhibitor of the DCN1-UBC12 interaction that selectively blocks cullin 3 neddylation. Zhou H et al., 2017 Oct 27, Nat Commun
    Read more