di-DTPA-LTL

MedChem Express

di-DTPA-LTL

14

Research Use Only

C52H82N12O23

1243.27

di-DTPA-LTL is a bivalent hapten based on tyrosine-containing polypeptide design. di-DTPA-LTL has good hydrophilia and biological distribution. di-DTPA-LTL is labeled with 111In (indium) and 131I (iodine). di-DTPA-LTL achieves tumor radioimmunoimaging in primary colorectal cancer patients with CEA by injecting a fixed low dose (5 mg) of bispecific antibody (anti-CEA x, anti-DTPA) and di-DTPA antigen peptide (labeled 111In) into the patients[1][2][3].

OC(CN(CCN(CC(O)=O)CCN(CC(NCCCC[C@@H](C(N[C@H](CC1=CC=C(O)C=C1)C(N[C@@H](CCCCNC(CN(CCN(CCN(CCC(O)=O)CC(O)=O)CC(O)=O)CC(O)=O)=O)C(N)=O)=O)=O)NC(C)=O)=O)CC(O)=O)CC(O)=O)=O

12131703