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DIBAC-GGFG-NH2CH2-Dxd [2758875-01-1]

HY-147363
MedChem Express
Product group Molecular Biology
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Overview

  • Supplier
    MedChem Express
  • Product Name
    DIBAC-GGFG-NH2CH2-Dxd [2758875-01-1]
  • Delivery Days Customer
    10
  • CAS Number
    2758875-01-1
  • Certification
    Research Use Only
  • Estimated Purity
    99.69
  • Molecular Formula
    C61H58FN9O12
  • Molecular Weight
    1128.16
  • Scientific Description
    DIBAC-GGFG-NH2CH2-Dxd (compound LP4), a Camptothecin (HY-16560) derivative, is a linker-payload of protein-agent conjugates[1]. Dxd (HY-13631D) can be used as a payload for the antibody-coupling drug ADC (DS-8201a).DIBAC-GGFG-NH2CH2-Dxd is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups[1][2].
  • SMILES
    O=C(N1C2=CC=CC=C2C#CC3=CC=CC=C3C1)CCC(NCC(NCC(N[C@@H](CC4=CC=CC=C4)C(NCC(NCOCC(N[C@@H]5C6=C7C(C(N8C7)=CC([C@](O)(C(OC9)=O)CC)=C9C8=O)=NC%10=CC(F)=C(C)C(CC5)=C%106)=O)=O)=O)=O)=O)=O
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    41115800