Dicer Antibody (OASE00264)

Aviva Systems Biology

Dicer Antibody (OASE00264)

23

ImmunoFluorescence, Western Blot, ImmunoCytoChemistry

Research Use Only

Monoclonal

S167-7

1 mg/ml

Unconjugated

Dicer1

dicer 1, ribonuclease type III

1110006F08Rik, D12Ertd7e, aviD, mKIAA0928, endoribonuclease Dicer, Dicer1, Dcr-1 homolog, double-strand-specific ribonuclease mDCR-1

Mouse

IgG1

Dicer is a member of the RNase III family that specifically cleaves double-stranded RNAs to generate microRNAs (miRNAs) (1). After long primary transcript pri-miRNAs are processed to stem-looped pre-miRNAs by Drosha (2), pre-miRNAs are transported to the cytoplasm and further processed by Dicer to produce 22-nucleotide mature miRNAs (3). The mature miRNA then becomes a part of the RNA-Induced Silencing Complex (RISC) and can bind to the 3 UTR of the target mRNA (3)

-20°C

12352203