Difamilast

MedChem Express

Difamilast [937782-05-3]

10

937782-05-3

Research Use Only

99.63

C23H24F2N2O5

446.44

Difamilast (OPA-15406) is a topical, selective and nonsteroidal phosphodiesterase-4 (PDE4) inhibitor with particularly efficient inhibition of subtype B ( IC 50 =11.2 nM). Difamilast can be used for the research of mild to moderate atopic dermatitis (AD) [1] [2] [3] .

CC(C)OC(C=C(C1=NC(CNC(C(C=CC=C2)=C2OCC)=O)=CO1)C=C3)=C3OC(F)F

-20°C,2°C to 8°C

12352200