Difluorinated Curcumin [1170354-22-9]

MedChem Express

Difluorinated Curcumin [1170354-22-9]

14

1170354-22-9

Research Use Only

C28H22F2O6

492.47

Difluorinated Curcumin (3,4-Difluorobenzylidene curcumin) is a fluorinated curcumin analog with high bioavailability and anticancer activity. Difluorinated Curcumin inhibits the self-renewal ability of tumor stem/stem-like cells, clonogenicity, invasiveness and angiogenesis of tumor cells. Difluorinated Curcumin also increases cell sensitivity to chemotherapy[1].

FC(C=C1/C=C(C(/C=C/C2=CC(OC)=C(C=C2)O)=O)/C(/C=C/C3=CC(OC)=C(C=C3)O)=O)=C(C=C1)F

-20°C

12352200