Dihydroberberine
HY-N1934
Overview
- SupplierMedChem Express
- Product NameDihydroberberine [483-15-8]
- Delivery Days Customer10
- CAS Number483-15-8
- CertificationResearch Use Only
- Estimated Purity98.44
- Molecular FormulaC20H19NO4
- Molecular Weight337.37
- Scientific DescriptionDihydroberberine is a naturally occurring isoquinoline alkaloid with anti-inflammatory, anti-atherosclerotic, hypolipidemic and anti-tumor activities. Dihydroberberine inhibits the human ether-related gene (hERG) channel and significantly reduces the expression of heat shock protein 90 (Hsp90) and its interaction with hERG. Dihydroberberine also blocks the TLR4/MyD88/NF-kappaB signaling pathway to reduce pro-inflammatory cytokines and immunoglobulins, and has inhibitory effects on DSS (HY-116282C)-induced experimental colitis. Dihydroberberine also increases the sensitivity of lung cancer to sunitinib (HY-10255A), with synergistic efficacy[1][2].
- SMILESCOC1=CC=C(C=C23)C(CN2CCC(C3=C4)=CC5=C4OCO5)=C1OC
- Storage Instruction2°C to 8°C
- UNSPSC12352200
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Product group Chemicals
CAS Number483-15-8
Estimated Purity0.9377
Molecular Weight337.37
- SizePrice
Product group Chemicals
DihydroberberineORB1299138
CAS Number483-15-8
Estimated Purity93.77%
Molecular Weight337.37
- SizePrice
