Dimethyl fumarate

MedChem Express

Dimethyl fumarate [624-49-7]

10

624-49-7

Research Use Only

99.99

C6H8O4

144.13

Dimethyl fumarate (DMF) is an orally active and brain-penetrant Nrf2 activator and induces upregulation of antioxidant gene expression. Dimethyl fumarate induces necroptosis in colon cancer cells through GSH depletion/ ROS increase/MAPKs activation pathway, and also induces cell autophagy . Dimethyl fumarate can be used for multiple sclerosis research [1] [2] .

O=C(OC)/C=C/C(OC)=O

-20°C,2°C to 8°C

12352200