Diminutol [361431-33-6]

TargetMol Chemicals

Diminutol [361431-33-6]

44

361431-33-6

Chemical

Research Use Only

Diminutol

C19H26N6OS

386.51

Diminutol is a cell-permeable purine derivative that inhibits the NADP-dependent oxidoreductase, NQO1 (Ki = 1.72 microM), to destabilize microtubules and disrupt mitosis. At 50 microM, it directly affects tubulin polymerization in Xenopus egg extracts without interfering with the activity of Cdk1, DNA replication, or actin polymerization.

3 years

S(C1=C2C(N(C(C)C)C=N2)=NC(N[C@H](C(C)C)CO)=N1)C3=CC(N)=CC=C3

-20°C

12352200