Dinaciclib

Selleck Chemicals

Dinaciclib (SCH727965) [779353-01-4]

9

779353-01-4

Research Use Only

...

Dinaciclib is a novel and potent CDK inhibitor for CDK2, CDK5, CDK1 and CDK9 with IC50 of 1 nM, 1 nM, 3 nM and 4 nM in cell-free assays, respectively. It also blocks thymidine (dThd) DNA incorporation. Dinaciclib induces apoptosis through the activation of caspases 8 and 9. Phase 3.

-80°C

51202000