Dinactin [20261-85-2]

MedChem Express

Dinactin [20261-85-2]

10

20261-85-2

Research Use Only

C42H68O12

764.98

Dinactin, an antibiotic ionophore produced by Streptomyces species, as an effective small molecule targeting Wnt/beta-catenin signaling pathway in cancer cells. Dinactin shows marked inhibition of HCT-116 cell growth with an IC50 of 1.1 microM. Dinactin shows anti-proliferative activity against the cancer cells in apoptosis-independent manner. Dinactin is also an effective agent for the research of neuropathic pain[1].

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