Diroximel fumarate

MedChem Express

Diroximel fumarate [1577222-14-0]

5

1577222-14-0

99.90

C11H13NO6

255.22

Diroximel fumarate (ALKS 8700) is an orally-active and well-tolerated monomethyl fumarate (MMF) proagent in a controlled-release formulation. Diroximel fumarate is considered as active equivalent to its active metabolite dimethyl fumarate (DMF). Diroximel fumarate has a favorable safety and efficacy profile, has the potential for the study of multiple sclerosis (MS). Diroximel fumarate is a Nrf2 activator that alleviate MGO-induced pain hypersensitivity [1] [2] .

O=C(OCCN1C(CCC1=O)=O)/C=C/C(OC)=O

-20°C,2°C to 8°C

12352200