
Immunohistochemistry of paraffin-embedded human ovarian tissue using CSB-PA818258LA01HU at dilution of 1:100
DIS3L2 Antibody
CSB-PA818258LA01HU
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
TargetDIS3L2
Overview
- SupplierCusabio
- Product NameDIS3L2 Antibody
- Delivery Days Customer20
- ApplicationsELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID129563
- Target nameDIS3L2
- Target descriptionDIS3 like 3'-5' exoribonuclease 2
- Target synonymsDIS3 mitotic control homolog-like 2; DIS3-like exonuclease 2; FAM6A; family with sequence similarity 6, member A; hDIS3L2; PRLMNS
- HostRabbit
- IsotypeIgG
- Protein IDQ8IYB7
- Protein NameDIS3-like exonuclease 2
- Scientific Description3-5-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3 end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase, such as ZCCHC11/TUT4. Mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3. Mediates degradation of uridylated pre-let-7 miRNAs, contributing to the maintenance of embryonic stem (ES) cells. Essential for correct mitosis, and negatively regulates cell proliferation.
- Storage Instruction-20°C or -80°C
- UNSPSC12352203