Bio-Connect
Western Blot Positive WB detected in: SH-SY5Y whole cell lysate, Hela whole cell lysate All lanes: DISC1 antibody at 2ug/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 94, 92, 74, 39, 83, 63, 61, 76, 73, 38, 22 kDa Observed band size: 94, 92, 38 kDa
Western Blot Positive WB detected in: SH-SY5Y whole cell lysate, Hela whole cell lysate All lanes: DISC1 antibody at 2ug/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 94, 92, 74, 39, 83, 63, 61, 76, 73, 38, 22 kDa Observed band size: 94, 92, 38 kDa
Western Blot Positive WB detected in: SH-SY5Y whole cell lysate, Hela whole cell lysate All lanes: DISC1 antibody at 2ug/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 94, 92, 74, 39, 83, 63, 61, 76, 73, 38, 22 kDa Observed band size: 94, 92, 38 kDa

DISC1 Antibody

Research Use Only
CSB-PA889093LA01HU
Cusabio
ApplicationsImmunoFluorescence, Western Blot, ELISA
Product group Antibodies
ReactivityHuman
TargetDISC1
Price on request
Packing Size
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    Cusabio
  • Product Name
    DISC1 Antibody
  • Delivery Days Customer
    20
  • Applications
    ImmunoFluorescence, Western Blot, ELISA
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID27185
  • Target name
    DISC1
  • Target description
    DISC1 scaffold protein
  • Target synonyms
    C1orf136; disrupted in schizophrenia 1 protein; SCZD9
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ9NRI5
  • Protein Name
    Disrupted in schizophrenia 1 protein
  • Scientific Description
    Involved in the regulation of multiple aspects of embryonic and adult neurogenesis. Required for neural progenitor proliferation in the ventrical/subventrical zone during embryonic brain development and in the adult dentate gyrus of the hippocampus. Participates in the Wnt-mediated neural progenitor proliferation as a positive regulator by modulating GSK3B activity and CTNNB1 abundance. Plays a role as a modulator of the AKT-mTOR signaling pathway controlling the tempo of the process of newborn neurons integration during adult neurogenesis, including neuron positioning, dendritic development and synapse formation. Inhibits the activation of AKT-mTOR signaling upon interaction with CCDC88A. Regulates the migration of early-born granule cell precursors toward the dentate gyrus during the hippocampal development. Plays a role, together with PCNT, in the microtubule network formation.
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C
  • UNSPSC
    12352203