DiSC2(5) (3, 3-diethylthiadicarboCyanine, iodide) [514-73-8]

Biotium

DiSC2(5) (3,3'-diethylthiadicarbocyanine, iodide)

9

514-73-8

Research Use Only

2811,6.1,Danger,ghs06 toxic (skull and crossbones), ghs07 exclamation mark,h300 fatal if swallowed. h315 causes skin irritation. h319 causes serious eye irritation.

DiSC2(5) (3,3-Diethylthiadicarbocyanine, iodide) binds to DNA-DNA or PNA-DNA duplexes with a large blue-shift of the absorption spectrum. Binding of the dye to PNA-DNA hybrid, in particular, blue-shifts the dye absorption spectrum by as much as 115 nm, offering a visual method to detect nucleic acid hybridization. lambdaAbs (pH 7.5 buffer) = 646 nm (free dye); ~586 nm (dsDNA); ~531 nm (PNA-DNA) Dark solid soluble in DMSO or MeOH Store at 4°C C23H23IN2S2 MW: 518.48

Synthetic

2°C to 8°C

41116134