Disulfiram

MedChem Express

Disulfiram [97-77-8]

10

97-77-8

Research Use Only

99.92

C10H20N2S4

296.54

Disulfiram (Tetraethylthiuram disulfide) is a specific inhibitor of aldehyde-dehydrogenase (ALDH1) , used for the treatment of chronic alcoholism by producing an acute sensitivity to alcohol. Disulfiram inhibits gasdermin D (GSDMD) pore formation in liposomes and inflammasome-mediated pyroptosis and IL-1beta secretion in human and mouse cells. Disulfiram, a copper ion carrier, with Cu 2+ increases intracellular ROS levels and induces cuproptosis [1] [2] [3] [4] [5] [6] .

S=C(SSC(N(CC)CC)=S)N(CC)CC

-20°C,2°C to 8°C

12352200