Dizocilpine [77086-21-6]

MedChem Express

Dizocilpine [77086-21-6]

10

77086-21-6

Research Use Only

99.95

C16H15N

221.30

Dizocilpine (MK-801), a potent anticonvulsant, is a selective and non-competitive NMDA receptor antagonist, with a Kd of 37.2 nM in rat brain membranes. Dizocilpine acts by binding to a site located within the NMDA associated ion channel and thus prevents Ca2+ flux[1][2].

C[C@]1(N2)C3=CC=CC=C3C[C@]2([H])C4=CC=CC=C14

-20°C

12131703