DK419 [2102672-22-8]

MedChem Express

DK419 [2102672-22-8]

9

2102672-22-8

Research Use Only

99.86

C16H8ClF6N3O

407.70

DK419 is a potent and orally active Wnt/beta-catenin signaling inhibitor, with an IC50 of 0.19 microM. DK419 reduces protein lelvels of Axin2, beta-catenin, c-Myc, Cyclin D1 and Survivin and induces production of pAMPK[1].

O=C(C1=C2C(N=C(C(F)(F)F)N2)=CC(Cl)=C1)NC3=CC=C(C(F)(F)F)C=C3

-20°C,2°C to 8°C

12352200